Annexin A6

ANXA6
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1M9I
Identifiers
Aliases	ANXA6, ANX6, CBP68, annexin A6, CPB-II, p70, p68
External IDs	OMIM: 114070; MGI: 88255; HomoloGene: 55558; GeneCards: ANXA6; OMA:ANXA6 - orthologs
Gene location (Human)
Chr.	Chromosome 5 (human)
End	151,157,785 bp
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)
End	54,924,271 bp
RNA expression pattern
	Top expressed in
	granulocyte; ; smooth muscle tissue; ; right coronary artery; ; apex of heart; ; stromal cell of endometrium; ; popliteal artery; ; muscle of thigh; ; tibial arteries; ; right ovary; ; gastric mucosa;
	Top expressed in
	internal carotid artery; ; external carotid artery; ; lactiferous gland; ; yolk sac; ; subcutaneous adipose tissue; ; muscle of thigh; ; facial motor nucleus; ; dermis; ; vestibular sensory epithelium; ; stroma of bone marrow;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	calcium ion binding; protein homodimerization activity; GTP binding; calcium-dependent protein binding; cholesterol binding; protein binding; ligand-gated ion channel activity; calcium-dependent phospholipid binding; lipid binding; phosphatidylserine binding; calcium channel activity; heparin binding; enzyme binding; chondroitin sulfate binding; signaling receptor activity; protein-containing complex binding; actin filament binding;
Cellular component	cytoplasm; membrane; late endosome membrane; focal adhesion; melanosome; lysosomal membrane; mitochondrion; perinuclear region of cytoplasm; extracellular exosome; collagen-containing extracellular matrix;
Biological process	regulation of muscle contraction; mitochondrial calcium ion homeostasis; ion transmembrane transport; apoptotic signaling pathway; protein homooligomerization; calcium ion transport; neural crest cell migration; plasma membrane repair; growth plate cartilage chondrocyte differentiation; biomineral tissue development; negative regulation of sequestering of calcium ion; calcium ion import; calcium ion transmembrane transport;
	Sources:Amigo / QuickGO
Orthologs
	309
	11749
	ENSG00000197043
	ENSMUSG00000018340
	P08133
	P14824
	NM_001155; NM_001193544; NM_004033; NM_001363114
	NM_001110211; NM_013472
	NP_001146; NP_001180473; NP_001350043
	NP_001103681; NP_038500
	Wikidata
View/Edit Human	View/Edit Mouse

Annexin A6 is a protein that in humans is encoded by the ANXA6 gene.^[5]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000197043 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000018340 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Crompton MR, Owens RJ, Totty NF, Moss SE, Waterfield MD, Crumpton MJ (Jan 1988). "Primary structure of the human, membrane-associated Ca2+-binding protein p68 a novel member of a protein family". The EMBO Journal. 7 (1): 21–7. doi:10.1002/j.1460-2075.1988.tb02779.x. PMC 454210. PMID 3258820.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000197043 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000018340 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid3258820-5] Crompton MR, Owens RJ, Totty NF, Moss SE, Waterfield MD, Crumpton MJ (Jan 1988). "Primary structure of the human, membrane-associated Ca2+-binding protein p68 a novel member of a protein family". The EMBO Journal. 7 (1): 21–7. doi:10.1002/j.1460-2075.1988.tb02779.x. PMC 454210. PMID 3258820.

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