| Anthranilate phosphoribosyltransferase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
 Anthranilate phosphoribosyltransferase homodimer, Mycobacterium tuberculosis | |||||||||
| Identifiers | |||||||||
| EC no. | 2.4.2.18 | ||||||||
| CAS no. | 9059-35-2 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
In enzymology, an anthranilate phosphoribosyltransferase (EC 2.4.2.18) is an enzyme that catalyzes the chemical reaction
- anthranilate + phosphoribosyl pyrophosphate N-(5-phosphoribosyl)-anthranilate + diphosphate
The two substrates of this enzyme are anthranilate and phosphoribosyl pyrophosphate. Its two products are N-(5-phosphoribosyl)-anthranilate and diphosphate.[1][2]
This enzyme participates in aromatic amino acid biosynthesis and two-component system (general).
- ^ C.A. Fulcher (2010-02-12). "Pathway: L-tryptophan biosynthesis". MetaCyc Metabolic Pathway Database. Retrieved 2022-02-17.
- ^ Crawford, Irving P. (1989). "Evolution of a Biosynthetic Pathway: The Tryptophan Paradigm". Annual Review of Microbiology. 43: 567–600. doi:10.1146/annurev.mi.43.100189.003031. PMID 2679363.