Antidepressants and suicide risk

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The relationship between antidepressant use and suicide risk is a subject of medical research and has faced varying levels of debate. This problem was thought to be serious enough to warrant intervention by the U.S. Food and Drug Administration to label greater likelihood of suicide as a risk of using antidepressants.^[1] Some studies have shown that the use of certain antidepressants correlate with an increased risk of suicide in some patients relative to other antidepressants.^[2] However, these conclusions have faced considerable scrutiny and disagreement: A multinational European study indicated that antidepressants decrease risk of suicide at the population level,^[3] and other reviews of antidepressant use claim that there is not enough data to indicate antidepressant use increases risk of suicide.^[4][5][6]