Apolipoprotein B

APOB
Identifiers
AliasesAPOB, FLDB, LDLCQ4, apoB-100, apoB-48, apolipoprotein B, FCHL2
External IDsOMIM: 107730; MGI: 88052; HomoloGene: 328; GeneCards: APOB; OMA:APOB - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_000384

NM_009693

RefSeq (protein)

NP_000375

NP_033823

Location (UCSC)Chr 2: 21 – 21.04 MbChr 12: 8.03 – 8.07 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Apolipoprotein B (ApoB) is a protein that in humans is encoded by the APOB gene. Its measurement is commonly used to detect risk of atherosclerotic cardiovascular disease.[5][6]

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000084674Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000020609Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Glavinovic T, Thanassoulis G, de Graaf J, Couture P, Hegele RA, Sniderman AD (October 2022). "Physiological Bases for the Superiority of Apolipoprotein B Over Low-Density Lipoprotein Cholesterol and Non-High-Density Lipoprotein Cholesterol as a Marker of Cardiovascular Risk". Journal of the American Heart Association. 11 (20): e025858. doi:10.1161/JAHA.122.025858. PMC 9673669. PMID 36216435.
  6. ^ Behbodikhah J, Ahmed S, Elyasi A, Kasselman LJ, De Leon J, Glass AD, Reiss AB (October 2021). "Apolipoprotein B and Cardiovascular Disease: Biomarker and Potential Therapeutic Target". Metabolites. 11 (10): 690. doi:10.3390/metabo11100690. PMC 8540246. PMID 34677405.