Arecoline

Arecoline
Clinical data
Other namesArecaline; Arecholine; Arecolin; Arecoline base; Arekolin; Methylarecaidin
ATC code
  • none
Legal status
Legal status
  • AU: S4 (Prescription only) [1]
  • UK: Could be illegal to sell for human consumption under the Psychoactive Substances Act or if is synthetized for recreational use[citation needed]
  • US: Unscheduled
Identifiers
  • Methyl 1-methyl-1,2,5,6-tetrahydropyridine-3-carboxylate
CAS Number
PubChem CID
IUPHAR/BPS
DrugBank
ChemSpider
UNII
KEGG
ChEBI
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.000.514 Edit this at Wikidata
Chemical and physical data
FormulaC8H13NO2
Molar mass155.197 g·mol−1
3D model (JSmol)
Density1.0495 g/cm3
Melting point27 °C (81 °F)
Boiling point209 °C (408 °F)
  • O=C(OC)C=1CN(C)CCC=1
  • InChI=1S/C8H13NO2/c1-9-5-3-4-7(6-9)8(10)11-2/h4H,3,5-6H2,1-2H3 checkY
  • Key:HJJPJSXJAXAIPN-UHFFFAOYSA-N checkY
 ☒NcheckY (what is this?)  (verify)

Arecoline (/əˈrɛkəln/) is a nicotinic acid-based mild parasympathomimetic stimulant alkaloid found in the areca nut, the fruit of the areca palm (Areca catechu).[2] It is an odourless oily liquid. It can bring a sense of enhanced alertness and energy along with mild feelings of euphoria and relaxation.

  1. ^ "Poisons Standard October 2020". Federal Register of Legislation. The Australian Government. 30 September 2020.
  2. ^ Ghelardini C, Galeotti N, Lelli C, Bartolini A (2001). "M1 receptor activation is a requirement for arecoline analgesia". Farmaco. 56 (5–7): 383–385. doi:10.1016/S0014-827X(01)01091-6. hdl:2158/327019. PMID 11482763.