Arkansas Highway 221

Highway 221
Route information
Maintained by AHTD
Length	18.25 mi[2] (29.37 km)
Existed	July 10, 1957[1]–present
Major junctions
South end	CR 1425 at the Madison County line
Major intersections	US 62 in Berryville AR 21 in Berryville
North end	Route 39 at the Missouri state line
Location
Country	United States
State	Arkansas
Counties	Carroll
Highway system
Arkansas Highway System Interstate US State Business Spurs Suffixed Scenic Heritage
← AR 220 → AR 222

Highway 221 (AR 221, Ark. 221, and Hwy. 221) is a north–south state highway in Carroll County, Arkansas. The route begins at the Madison County line and runs north through Berryville to the Missouri state line. Created in 1957, the route has remained unchanged since 1967. The route is maintained by the Arkansas State Highway and Transportation Department (AHTD).