Aromatic L-amino acid decarboxylase

DOPA decarboxylase (aromatic L-amino acid decarboxylase)
DOPA decarboxylase (aromatic L-amino acid decarboxylase)
	Aromatic L-amino acid decarboxylase homodimer, Human
Identifiers
Symbol	DDC
NCBI gene	1644
HGNC	2719
OMIM	107930
RefSeq	NM_000790
UniProt	P20711
Other data
EC number	4.1.1.28
Locus	Chr. 7 p11
Structures
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Structures	Swiss-model
Domains	InterPro

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Aromatic L-amino acid decarboxylase (DOPA decarboxylase)
Aromatic L-amino acid decarboxylase (DOPA decarboxylase)
	Ribbon diagram of a DOPA decarboxylase dimer.
Identifiers
EC no.	4.1.1.28
CAS no.	9042-64-2
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Gene Ontology	AmiGO / QuickGO
PMC
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PMC	articles
PubMed	articles
NCBI	proteins

Aromatic L-amino acid decarboxylase (AADC or AAAD), also known as DOPA decarboxylase (DDC), tryptophan decarboxylase, and 5-hydroxytryptophan decarboxylase, is a lyase enzyme (EC 4.1.1.28), located in region 7p12.2-p12.1.

^ PDB: 1JS3; Burkhard P, Dominici P, Borri-Voltattorni C, Jansonius JN, Malashkevich VN (November 2001). "Structural insight into Parkinson's disease treatment from drug-inhibited DOPA decarboxylase". Nature Structural Biology. 8 (11): 963–7. doi:10.1038/nsb1101-963. PMID 11685243. S2CID 19160912.

[pmid11685243-1] PDB: 1JS3; Burkhard P, Dominici P, Borri-Voltattorni C, Jansonius JN, Malashkevich VN (November 2001). "Structural insight into Parkinson's disease treatment from drug-inhibited DOPA decarboxylase". Nature Structural Biology. 8 (11): 963–7. doi:10.1038/nsb1101-963. PMID 11685243. S2CID 19160912.

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