Arsphenamine

The structure of arsphenamine has been proposed to be akin to azobenzene (A), but chemical studies published in 2005 suggest[1] that salvarsan is actually a mixture of the trimer (B) and the pentamer (C).

Arsphenamine, also known as Salvarsan or compound 606, is an antibiotic drug that was introduced at the beginning of the 1910s as the first effective treatment for the deadly infectious diseases syphilis, relapsing fever, and African trypanosomiasis.[2][3] This organoarsenic compound was the first modern antimicrobial agent.[4]

  1. ^ Cite error: The named reference pmid15624113 was invoked but never defined (see the help page).
  2. ^ Gibaud, Stéphane; Jaouen, Gérard (2010). "Arsenic-Based Drugs: From Fowler's Solution to Modern Anticancer Chemotherapy". Medicinal Organometallic Chemistry. Topics in Organometallic Chemistry. Vol. 32. pp. 1–20. Bibcode:2010moc..book....1G. doi:10.1007/978-3-642-13185-1_1. ISBN 978-3-642-13184-4.
  3. ^ Ehrlich, Paul; Hata, Sahachiro; Newbold, A.; Felkin, Robert W. (1911). The Experimental Chemotherapy of Spirilloses. New York: Rebman. OCLC 3225081.
  4. ^ Cite error: The named reference Williams was invoked but never defined (see the help page).