The Ashcroft First Nation (Thompson: sƛ̓ə́z) is a First Nations government Thompson Canyon area of the Central Interior of the Canadian province of British Columbia. Its Indian Reserves are located near the town of Ashcroft, British Columbia, it is a member of the Nlaka'pamux Nation Tribal Council.
Other Nlaka'pamux bands belong to the Nicola Tribal Association or the Fraser Canyon Indian Administration.