Astruc (Hebrew: אסטרוק) is a Jewish surname and a given name (praenomen).[1][2][3] In Provençal dialect, astruc means "happy", "lucky".[4] Notable people with the name include:
- Astruc family
- Abba Mari (13th century), French rabbi who took the name Astruc
- Astruc de Noves (14th century), French philosopher and physicist
- Astruc Remoch (14th century), Spanish medieval doctor
- Astruc ha-Levi (14th century), Spanish medieval scholar
- Alexandre Astruc (1923–2016), French film critic and director
- Didier Astruc, French chemist
- Gabriel Astruc (1864–1938), French theatrical impresario
- Jean Astruc (1684–1766), French medical professor
- Miriam Astruc (1904–1963), French archaeologist
- Mordecai Astruc (fl. late 17th century), Jewish liturgical poet
- Zacharie Astruc (1835–1907), French sculptor, painter and author