Autolysis in winemaking relates to the complex chemical reactions that take place when a wine spends time in contact with the lees, or dead yeast cells, after fermentation. While for some wines - and all beers[1] - autolysis is undesirable, it is a vital component in shaping the flavors and mouth feel associated with premium Champagne production.[2][3] The practice of leaving a wine to age on its lees (or sur lie aging) has a long history in winemaking dating back to Roman winemaking. The chemical process and details of autolysis were not originally understood scientifically, but the positive effects such as a creamy mouthfeel, breadlike and floral aromas, and reduced astringency were noticed early in the history of wine.[4]