B-cell activating factor

TNFSF13B
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesTNFSF13B, BAFF, BLYS, CD257, DTL, TALL-1, TALL1, THANK, TNFSF20, ZTNF4, TNLG7A, tumor necrosis factor superfamily member 13b, TNF superfamily member 13b
External IDsOMIM: 603969; MGI: 1344376; HomoloGene: 48443; GeneCards: TNFSF13B; OMA:TNFSF13B - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001145645
NM_006573

NM_033622
NM_001347309

RefSeq (protein)

NP_001139117
NP_006564

NP_001334238
NP_296371

Location (UCSC)Chr 13: 108.25 – 108.31 MbChr 8: 10.06 – 10.09 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

B-cell activating factor (BAFF) also known as tumor necrosis factor ligand superfamily member 13B and CD257 among other names, is a protein that in humans is encoded by the TNFSF13B gene.[5][6] BAFF is also known as B Lymphocyte Stimulator (BLyS) and TNF- and APOL-related leukocyte expressed ligand (TALL-1) and the Dendritic cell-derived TNF-like molecule (CD257 antigen; cluster of differentiation 257).

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000102524Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000031497Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Shu HB, Hu WH, Johnson H (May 1999). "TALL-1 is a novel member of the TNF family that is down-regulated by mitogens". Journal of Leukocyte Biology. 65 (5): 680–3. doi:10.1002/jlb.65.5.680. PMID 10331498. S2CID 1498303.
  6. ^ Schneider P, MacKay F, Steiner V, Hofmann K, Bodmer JL, Holler N, Ambrose C, Lawton P, Bixler S, Acha-Orbea H, Valmori D, Romero P, Werner-Favre C, Zubler RH, Browning JL, Tschopp J (June 1999). "BAFF, a novel ligand of the tumor necrosis factor family, stimulates B cell growth". The Journal of Experimental Medicine. 189 (11): 1747–56. doi:10.1084/jem.189.11.1747. PMC 2193079. PMID 10359578.