BAFF receptor

TNFRSF13C
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesTNFRSF13C, BAFF-R, BAFFR, BROMIX, CD268, CVID4, prolixin, tumor necrosis factor receptor superfamily member 13C, TNF receptor superfamily member 13C
External IDsOMIM: 606269; MGI: 1919299; HomoloGene: 49897; GeneCards: TNFRSF13C; OMA:TNFRSF13C - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_052945

NM_028075
NM_001357758

RefSeq (protein)

NP_443177

NP_082351
NP_001344687

Location (UCSC)Chr 22: 41.92 – 41.93 MbChr 15: 82.11 – 82.11 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

BAFF receptor (B-cell activating factor receptor, BAFF-R), also known as tumor necrosis factor receptor superfamily member 13C (TNFRSF13C) and BLyS receptor 3 (BR3), is a membrane protein of the TNF receptor superfamily which recognizes BAFF, an essential factor for B cell maturation and survival.[5][6] In humans it is encoded by the TNFRSF13C gene.[7]

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000159958Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000068105Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Thompson JS, Bixler SA, Qian F, Vora K, Scott ML, Cachero TG, Hession C, Schneider P, Sizing ID, Mullen C, Strauch K, Zafari M, Benjamin CD, Tschopp J, Browning JL, Ambrose C (September 2001). "BAFF-R, a newly identified TNF receptor that specifically interacts with BAFF". Science. 293 (5537): 2108–11. Bibcode:2001Sci...293.2108T. doi:10.1126/science.1061965. PMID 11509692. S2CID 42673198.
  6. ^ Yan M, Brady JR, Chan B, Lee WP, Hsu B, Harless S, Cancro M, Grewal IS, Dixit VM (October 2001). "Identification of a novel receptor for B lymphocyte stimulator that is mutated in a mouse strain with severe B cell deficiency". Current Biology. 11 (19): 1547–52. Bibcode:2001CBio...11.1547Y. doi:10.1016/S0960-9822(01)00481-X. PMID 11591325. S2CID 13925100.
  7. ^ "Entrez Gene: TNFRSF13C tumor necrosis factor receptor superfamily, member 13C".