BAIAP2

BAIAP2
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1WDZ, 1Y2O, 2YKT, 3RNJ, 4JS0
Identifiers
Aliases	BAIAP2, BAP2, FLAF3, IRSP53, BAI1 associated protein 2, BAR/IMD domain containing adaptor protein 2, WAML
External IDs	OMIM: 605475; MGI: 2137336; HomoloGene: 9697; GeneCards: BAIAP2; OMA:BAIAP2 - orthologs
Gene location (Human)
Chr.	Chromosome 17 (human)
End	81,117,432 bp
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)
End	119,897,608 bp
RNA expression pattern
	Top expressed in
	Brodmann area 10; ; frontal pole; ; middle frontal gyrus; ; right frontal lobe; ; skin of abdomen; ; anterior cingulate cortex; ; skin of leg; ; Brodmann area 9; ; caudate nucleus; ; nucleus accumbens;
	Top expressed in
	superior frontal gyrus; ; olfactory tubercle; ; dentate gyrus of hippocampal formation granule cell; ; primary visual cortex; ; piriform cortex; ; corneal stroma; ; nucleus accumbens; ; perirhinal cortex; ; entorhinal cortex; ; primary motor cortex;
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	PDZ domain binding; protein C-terminus binding; protein binding; identical protein binding; cytoskeletal anchor activity; proline-rich region binding; cadherin binding involved in cell-cell adhesion; transcription coregulator binding; scaffold protein binding;
Cellular component	cytosol; cell projection; postsynaptic density; membrane; filopodium; ruffle; dendritic spine; secretory granule; soma; actin cytoskeleton; neuron projection; extracellular exosome; cytoskeleton; cytoplasm; rough endoplasmic reticulum; Golgi apparatus; microtubule; plasma membrane; dendritic shaft; neuron projection terminus; excitatory synapse; synaptic membrane; postsynapse; neuron projection branch point; dendritic spine cytoplasm; presynapse; nucleoplasm; Schaffer collateral - CA1 synapse; glutamatergic synapse; postsynaptic density, intracellular component; presynaptic cytosol; postsynaptic cytosol;
Biological process	insulin receptor signaling pathway; positive regulation of actin filament polymerization; regulation of actin cytoskeleton organization; response to bacterium; axonogenesis; Fc-gamma receptor signaling pathway involved in phagocytosis; dendrite development; actin filament bundle assembly; regulation of synaptic plasticity; vascular endothelial growth factor receptor signaling pathway; actin crosslink formation; regulation of cell shape; plasma membrane organization; positive regulation of actin cytoskeleton reorganization; positive regulation of dendritic spine morphogenesis; cell-cell adhesion; brain development; positive regulation of neuron projection development; neuron differentiation; protein localization to synapse; cellular response to epidermal growth factor stimulus; cellular response to L-glutamate; positive regulation of excitatory postsynaptic potential; modulation of chemical synaptic transmission; modification of synaptic structure, modulating synaptic transmission; regulation of modification of postsynaptic actin cytoskeleton;
	Sources:Amigo / QuickGO
Orthologs
	10458
	108100
	ENSG00000175866
	ENSMUSG00000025372
	Q9UQB8
	Q8BKX1
	NM_001144888; NM_006340; NM_017450; NM_017451
	NM_001037754; NM_001037755; NM_130862
	NP_001138360; NP_006331; NP_059344; NP_059345
	NP_001032843; NP_001032844; NP_570932
	Wikidata
View/Edit Human	View/Edit Mouse

Brain-specific angiogenesis inhibitor 1-associated protein 2 is a protein that in humans is encoded by the BAIAP2 gene.^[5]^[6]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000175866 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000025372 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Oda K, Shiratsuchi T, Nishimori H, Inazawa J, Yoshikawa H, Taketani Y, Nakamura Y, Tokino T (June 1999). "Identification of BAIAP2 (BAI-associated protein 2), a novel human homologue of hamster IRSp53, whose SH3 domain interacts with the cytoplasmic domain of BAI1". Cytogenet Cell Genet. 84 (1–2): 75–82. doi:10.1159/000015219. PMID 10343108. S2CID 27688560.
^ Cite error: The named reference entrez was invoked but never defined (see the help page).

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000175866 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000025372 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid10343108-5] Oda K, Shiratsuchi T, Nishimori H, Inazawa J, Yoshikawa H, Taketani Y, Nakamura Y, Tokino T (June 1999). "Identification of BAIAP2 (BAI-associated protein 2), a novel human homologue of hamster IRSp53, whose SH3 domain interacts with the cytoplasmic domain of BAI1". Cytogenet Cell Genet. 84 (1–2): 75–82. doi:10.1159/000015219. PMID 10343108. S2CID 27688560.

[entrez-6] Cite error: The named reference entrez was invoked but never defined (see the help page).

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