BCL9

BCL9
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2GL7, 2VP7, 2VPB, 2VPD, 2VPE, 2VPG, 3SL9
Identifiers
Aliases	BCL9, LGS, B-cell CLL/lymphoma 9, B cell CLL/lymphoma 9, transcription coactivator, BCL9 transcription coactivator
External IDs	OMIM: 602597; MGI: 1924828; HomoloGene: 3191; GeneCards: BCL9; OMA:BCL9 - orthologs
Gene location (Human)
Chr.	Chromosome 1 (human)
End	147,626,216 bp
Gene location (Mouse)
Chr.	Chromosome 3 (mouse)
End	97,205,233 bp
RNA expression pattern
	Top expressed in
	ganglionic eminence; ; ventricular zone; ; islet of Langerhans; ; right uterine tube; ; smooth muscle tissue; ; left uterine tube; ; body of uterus; ; cerebellar cortex; ; cerebellar hemisphere; ; cardia;
	Top expressed in
	genital tubercle; ; tail of embryo; ; zygote; ; Rostral migratory stream; ; ventricular zone; ; neural layer of retina; ; ganglionic eminence; ; secondary oocyte; ; neural tube; ; Paneth cell;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	beta-catenin binding; protein binding; transcription coactivator activity;
Cellular component	cytoplasm; cis-Golgi network; Golgi apparatus; nucleus; nucleoplasm; beta-catenin-TCF complex;
Biological process	skeletal muscle cell differentiation; canonical Wnt signaling pathway; Wnt signaling pathway; somatic stem cell population maintenance; myotube differentiation involved in skeletal muscle regeneration; positive regulation of transcription by RNA polymerase II; regulation of transforming growth factor beta receptor signaling pathway; beta-catenin-TCF complex assembly;
	Sources:Amigo / QuickGO
Orthologs
	607
	77578
	ENSG00000116128
	ENSMUSG00000038256
	O00512
	Q9D219
	NM_004326
	NM_029933
	NP_004317
	NP_084209
	Wikidata
View/Edit Human	View/Edit Mouse

B-cell CLL/lymphoma 9 protein is a protein that in humans is encoded by the BCL9 gene.^[5]^[6]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000116128 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000038256 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Willis TG, Zalcberg IR, Coignet LJ, Wlodarska I, Stul M, Jadayel DM, et al. (March 1998). "Molecular cloning of translocation t(1;14)(q21;q32) defines a novel gene (BCL9) at chromosome 1q21". Blood. 91 (6): 1873–1881. doi:10.1182/blood.V91.6.1873. PMID 9490669.
^ "Entrez Gene: BCL9 B-cell CLL/lymphoma 9".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000116128 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000038256 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid9490669-5] Willis TG, Zalcberg IR, Coignet LJ, Wlodarska I, Stul M, Jadayel DM, et al. (March 1998). "Molecular cloning of translocation t(1;14)(q21;q32) defines a novel gene (BCL9) at chromosome 1q21". Blood. 91 (6): 1873–1881. doi:10.1182/blood.V91.6.1873. PMID 9490669.

[entrez-6] "Entrez Gene: BCL9 B-cell CLL/lymphoma 9".

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