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Babe Ruth (1895–1948) was an American baseball outfielder and pitcher who played 22 seasons in Major League Baseball (MLB), from 1914 to 1935.
Babe Ruth may also refer to:
- Babe Ruth (band), a British rock band
- Babe Ruth Award, a baseball award
- Babe Ruth (film), a 1991 American drama film
- Ruth Cleveland, first daughter of US President Grover Cleveland