Bacterial circadian rhythm

Bacterial circadian rhythms, like other circadian rhythms, are endogenous "biological clocks" that have the following three characteristics: (a) in constant conditions (i.e. constant temperature and either constant light {LL} or constant darkness {DD}) they oscillate with a period that is close to, but not exactly, 24 hours in duration, (b) this "free-running" rhythm is temperature compensated, and (c) the rhythm will entrain to an appropriate environmental cycle.

Until the mid-1980s, it was thought that only eukaryotic cells had circadian rhythms. It is now known that cyanobacteria (a phylum of photosynthetic eubacteria) have well-documented circadian rhythms that meet all the criteria of bona fide circadian rhythms. In these bacteria, three key proteins whose structures have been determined, KaiA, KaiB, and KaiC can form a molecular clockwork that orchestrates global gene expression.[1] This system enhances the fitness of cyanobacteria in rhythmic environments.

  1. ^ Ishiura M, Kutsuna S, Aoki S, Iwasaki H, Andersson CR, Tanabe A, Golden SS, Johnson CH, Kondo T (September 1998). "Expression of a gene cluster kaiABC as a circadian feedback process in cyanobacteria". Science. 281 (5382): 1519–23. doi:10.1126/science.281.5382.1519. PMID 9727980.