| Baculoviridae | |
|---|---|
| |
| Baculovirus virions and nucleocapsids | |
Virus classification 
| |
| (unranked): | Virus |
| Class: | Naldaviricetes |
| Order: | Lefavirales |
| Family: | Baculoviridae |
| Genera | |
Baculoviridae is a family of viruses. Arthropods, among the most studied being Lepidoptera, Hymenoptera and Diptera, serve as natural hosts. Currently, 85 species are placed in this family, assigned to four genera.[1][2][3]
Baculoviruses are known to infect insects, with over 600 host species having been described. Immature (larval) forms of lepidopteran species (moths and butterflies) are the most common hosts, but these viruses have also been found infecting sawflies, and mosquitoes. Although baculoviruses are capable of entering mammalian cells in culture,[4] they are not known to be capable of replication in mammalian or other vertebrate animal cells.
Starting in the 1940s, they were used and studied widely as biopesticides in crop fields. Baculoviruses contain a circular, double-stranded DNA (dsDNA) genome ranging from 80 to 180 kbp.
- ^ Harrison, RL; Herniou, EA; Jehle, JA; Theilmann, DA; Burand, JP; Becnel, JJ; Krell, PJ; van Oers, MM; Mowery, JD; Bauchan, GR; Ictv Report, Consortium (September 2018). "ICTV Virus Taxonomy Profile: Baculoviridae". The Journal of General Virology. 99 (9): 1185–1186. doi:10.1099/jgv.0.001107. PMID 29947603.
- ^ "Viral Zone". ExPASy. Archived from the original on 2 May 2017. Retrieved 15 June 2015.
- ^ "Virus Taxonomy: 2020 Release". International Committee on Taxonomy of Viruses (ICTV). March 2021. Archived from the original on 20 March 2020. Retrieved 12 May 2021.
- ^ Hofmann, C.; Sandig, V.; Jennings, G.; Rudolph, M.; Schlag, P.; Strauss, M. (1995). "Efficient Gene Transfer into Human Hepatocytes by Baculovirus Vectors". Proceedings of the National Academy of Sciences. 92 (22): 10099–10103. Bibcode:1995PNAS...9210099H. doi:10.1073/pnas.92.22.10099. PMC 40743. PMID 7479733.