Barrier to autointegration factor 1

BANF1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1QCK, 2ODG, 1CI4, 2BZF, 2EZY, 2EZZ, 2EZX
Identifiers
Aliases	BANF1, BAF, BCRP1, D14S1460, NGPS, Barrier to autointegration factor 1, BAF nuclear assembly factor 1
External IDs	OMIM: 603811; MGI: 1346330; HomoloGene: 2866; GeneCards: BANF1; OMA:BANF1 - orthologs
Gene location (Human)
Chr.	Chromosome 11 (human)
End	66,004,149 bp
Gene location (Mouse)
Chr.	Chromosome 19 (mouse)
End	5,417,196 bp
RNA expression pattern
	Top expressed in
	ganglionic eminence; ; ventricular zone; ; right uterine tube; ; muscle of thigh; ; apex of heart; ; gastrocnemius muscle; ; ascending aorta; ; body of uterus; ; Descending thoracic aorta; ; right coronary artery;
	Top expressed in
	somite; ; embryo; ; medial ganglionic eminence; ; mandibular prominence; ; maxillary prominence; ; epiblast; ; embryo; ; thymus; ; fetal liver hematopoietic progenitor cell; ; hand;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	DNA binding; protein binding; protein C-terminus binding; enzyme binding; protein homodimerization activity; protein N-terminus binding; LEM domain binding; identical protein binding;
Cellular component	cytoplasm; extracellular exosome; condensed chromosome; nucleus; chromosome; nucleoplasm; cytosol; nuclear envelope;
Biological process	mitotic nuclear membrane reassembly; response to virus; mitotic nuclear membrane disassembly; DNA integration; establishment of integrated proviral latency; viral process; nuclear transport; negative regulation of viral genome replication; chromosome segregation; chromosome condensation;
	Sources:Amigo / QuickGO
Orthologs
	8815
	23825
	ENSG00000175334
	ENSMUSG00000024844
	O75531
	O54962
	NM_003860; NM_001143985
	NM_001038231; NM_001286608; NM_011793
	NP_001137457; NP_003851
	NP_001033320; NP_001273537; NP_035923
	Wikidata
View/Edit Human	View/Edit Mouse

Barrier-to-autointegration factor is a protein that in humans is encoded by the BANF1 gene.^[5]^[6] It is a member of the barrier-to-autointegration factor family of proteins.

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000175334 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000024844 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Lee MS, Craigie R (Mar 1998). "A previously unidentified host protein protects retroviral DNA from autointegration". Proc Natl Acad Sci U S A. 95 (4): 1528–33. Bibcode:1998PNAS...95.1528L. doi:10.1073/pnas.95.4.1528. PMC 19075. PMID 9465049.
^ "Entrez Gene: BANF1 barrier to autointegration factor 1".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000175334 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000024844 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid9465049-5] Lee MS, Craigie R (Mar 1998). "A previously unidentified host protein protects retroviral DNA from autointegration". Proc Natl Acad Sci U S A. 95 (4): 1528–33. Bibcode:1998PNAS...95.1528L. doi:10.1073/pnas.95.4.1528. PMC 19075. PMID 9465049.

[entrez-6] "Entrez Gene: BANF1 barrier to autointegration factor 1".

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