| Basidiobolomycosis | |
|---|---|
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| Basidiobolus ranarum: causative organism | |
| Specialty | Infectious disease[1] |
| Symptoms | Firm painless nodule in skin,[2] tummy upset[3] |
| Complications | Spread to local structures[2] |
| Usual onset | Gradual/slow[2] |
| Causes | B. ranarum[2] |
| Diagnostic method | Medical imaging, biopsy, microscopy, culture, histopathology[2] |
| Differential diagnosis | Inflammatory bowel disease[2] |
| Treatment | Antifungals, surgery[4] |
| Medication | Amphotericin B[4] |
| Frequency | Rare[3] |
Basidiobolomycosis is a fungal disease caused by Basidiobolus ranarum.[1][5] It may appear as one or more painless firm nodules in the skin which becomes purplish with an edge that appears to be slowly growing outwards.[3][5] A serious but less common type affects the stomach and intestine, which usually presents with abdominal pain, fever and a mass.[3]
B. ranarum, can be found in soil, decaying vegetables and has been isolated from insects, some reptiles, amphibians, and mammals.[2] The disease results from direct entry of the fungus through broken skin such as an insect bite or trauma, or eating contaminated food.[1][3] It generally affects people who are well.[2]
Diagnosis is by medical imaging, biopsy, microscopy, culture and histopathology.[2] Treatment usually involves amphotericin B and surgery.[3][4]
Although B. ranarum is found around the world, the disease Basidiobolomycosis is generally reported in tropical and subtropical areas of Africa, South America, Asia and Southwestern United States.[3] It is rare.[3] The first case in a human was reported from Indonesia in 1956 as a skin infection.[4]
- ^ a b c Al Jarie, A.; Al Azraki, T.; Al Mohsen, I.; Al Jumaah, S.; Almutawa, A.; Mohd Fahim, Y.; Al Shehri, M.; Abu Dayah, A.; Ibrahim, A.; Maw Shabana, M.; Rezk Abd-Elwahed Hussein, M. (March 2011). "Basidiobolomycosis: Case series". Journal de Mycologie Médicale. 21 (1): 37–45. doi:10.1016/j.mycmed.2010.11.002. ISSN 1156-5233. PMID 24451502.
- ^ a b c d e f g h i Queiroz-Telles, Flavio; Fahal, Ahmed Hassan; Falci, Diego R.; Caceres, Diego H.; Chiller, Tom; Pasqualotto, Alessandro C. (November 2017). "Neglected endemic mycoses". The Lancet. Infectious Diseases. 17 (11): e367–e377. doi:10.1016/S1473-3099(17)30306-7. ISSN 1474-4457. PMID 28774696.
- ^ a b c d e f g h Bering, Jamie; Mafi, Neema; Vikram, Holenarasipur R. (May 2018). "Basidiobolomycosis: an unusual, mysterious, and emerging endemic fungal infection". Paediatrics and International Child Health. 38 (2): 81–84. doi:10.1080/20469047.2018.1458772. ISSN 2046-9055. PMID 29846151. S2CID 44181507.
- ^ a b c d Cite error: The named reference
Geram2015was invoked but never defined (see the help page). - ^ a b "ICD-11 - ICD-11 for Mortality and Morbidity Statistics". icd.who.int. Retrieved 22 May 2021.