Basophilia | |
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Basophilic Granulocyte surrounded by Erythrocytes and a Thrombocyte. | |
Pronunciation |
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Specialty | Hematology |
Causes | Chronic myeloid leukemia, polycythemia vera, primary myelofibrosis, essential thrombocythemia, acute myeloid leukemia, allergic reactions or chronic inflammation related to infections, inflammatory bowel disease, and autoimmune disease. |
Diagnostic method | Complete blood count and blood smear. |
Basophilia is the condition of having greater than 200 basophils/μL in the venous blood.[1] Basophils are the least numerous of the myelogenous cells, and it is rare for their numbers to be abnormally high without changes to other blood components. Rather, basophilia is most often coupled with other white blood cell conditions such as eosinophilia, high levels of eosinophils in the blood.[1] Basophils are easily identifiable by a blue coloration of the granules within each cell, marking them as granulocytes, in addition to segmented nuclei.[2]