Benign cephalic histiocytosis

See also: Neonatal cephalic pustulosis
Benign cephalic histiocytosis
Other namesHistiocytosis with intracytoplasmic worm-like bodies[1]
SpecialtyHematology Edit this on Wikidata

Benign cephalic histiocytosis (BCH) is a non-Langerhan's histiocytosis that is uncommon and self-limiting, usually beginning towards the end of the first year of life.[2] Gianotti et al. originally described it in 1971.[3] Initially affecting the head and neck, this condition is characterized by several small eruptions of yellow to reddish-brown papules that heal on their own.[4] Histological investigations have demonstrated that this disorder is associated with dermal proliferation of histiocytes, characterized by intracytoplasmic comma-shaped bodies, covered vesicles, and desmosome-like structure.[3]

  1. ^ Rapini, Ronald P.; Bolognia, Jean L.; Jorizzo, Joseph L. (2007). Dermatology: 2-Volume Set. St. Louis: Mosby. ISBN 978-1-4160-2999-1.
  2. ^ Peña-Penabad, Carmen; Unamuno, Pablo; Garcia-Silva, Jesús; Ludeña, M. Dolores; Armijo, Miguel (1994). "Benign Cephalic Histiocytosis: Case Report and Literature Review". Pediatric Dermatology. 11 (2). Wiley: 164–167. doi:10.1111/j.1525-1470.1994.tb00573.x. ISSN 0736-8046. PMID 8041659. S2CID 21634782.
  3. ^ a b Jih, Debra M.; Salcedo, Stephen L.; Jaworsky, Christine (2002). "Benign cephalic histiocytosis: A case report and review". Journal of the American Academy of Dermatology. 47 (6). Elsevier BV: 908–913. doi:10.1067/mjd.2002.124602. ISSN 0190-9622. PMID 12451377.
  4. ^ Koca, Rafet; Bektaş, Sibel; Altinyazar, H. Cevdet; Sezer, Tuna (2011). "Benign Cephalic Histiocytosis: A Case Report". Annals of Dermatology. 23 (4). Korean Dermatological Association and The Korean Society for Investigative Dermatology: 508–511. doi:10.5021/ad.2011.23.4.508. ISSN 1013-9087. PMC 3229948. PMID 22148022.