Big Lick may refer to:
- Big Lick, North Carolina, a populated place
- Big Lick, Virginia, a former name of Roanoke
- A "big lick" gait is an unnaturally exaggerated horse movement of a Tennessee Walking Horse created by illegal soring
- The HD-2 channel of WCLT-FM, a radio station (100.3 FM) licensed to Newark, Ohio, United States
- A galaxy group consisting of NGC 5371 and Hickson 68
This disambiguation page lists articles associated with the title Big Lick.
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