Bik Kwoon Tye | |
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Alma mater | Wellesley College (B.A)
University of California, San Francisco (UCSF) (M.Sc.) Massachusetts Institute of Technology (Ph.D.) |
Known for | Okazaki fragment generation during aberrant DNA repair in E. coli, Minichromosome maintenance genes (MCM) in yeast, High-resolution structures of MCM complexes and origin recognition complex (ORC) |
Spouse | Henry Sze-Hoi Tye |
Children | 2 |
Awards | Helen Hay Whitney Postdoctoral Research Fellowship (1974–1977). Elected to the National Academy of Sciences (2023). |
Scientific career | |
Fields | Molecular Genetics, Structural Biology |
Institutions | Cornell University, Hong Kong University of Science & Technology |
Doctoral advisor | David Botstein and Joel Huberman |
Bik Kwoon Yeung Tye (Chinese: 戴楊碧瓘; born c. 1947) is a Chinese-American molecular geneticist and structural biologist. Tye's pioneering work on eukaryotic DNA replication led to the discovery of the minichromosome maintenance (MCM) genes in 1984,[1] which encode the catalytic core of the eukaryotic replisome. Tye also determined the first high-resolution structures of both the MCM complex[2] and the Origin Recognition Complex (ORC)[3] in 2015 and 2018. Tye is currently a Professor Emeritus (2015) at Cornell University[4] and a visiting professor at the Hong Kong University of Science & Technology.[5] She is married to Henry Sze-Hoi Tye and is the mother of Kay Tye[6] and Lynne Tye.[7]