Biological data visualization

Biological data visualization is a branch of bioinformatics concerned with the application of computer graphics, scientific visualization, and information visualization to different areas of the life sciences. This includes visualization of sequences, genomes, alignments, phylogenies, macromolecular structures, systems biology, microscopy, and magnetic resonance imaging data. Software tools used for visualizing biological data range from simple, standalone programs to complex, integrated systems.

An emerging trend is the blurring of boundaries between the visualization of 3D structures at atomic resolution, the visualization of larger complexes by cryo-electron microscopy, and the visualization of the location of proteins and complexes within whole cells and tissues.[1][2] There has also been an increase in the availability and importance of time-resolved data from systems biology, electron microscopy, and cell and tissue imaging.[3][4]

  1. ^ Lucić V, Förster F, Baumeister W (2005). "Structural studies by electron tomography: from cells to molecules". Annual Review of Biochemistry. 74: 833–65. doi:10.1146/annurev.biochem.73.011303.074112. PMID 15952904.
  2. ^ Steven AC, Baumeister W (September 2008). "The future is hybrid". Journal of Structural Biology. 163 (3): 186–95. doi:10.1016/j.jsb.2008.06.002. PMID 18602011. S2CID 2432954.
  3. ^ Plattner H, Hentschel J (2006). "Sub-Second Cellular Dynamics: Time-Resolved Electron Microscopy and Functional Correlation". A Survey of Cell Biology (Submitted manuscript). International Review of Cytology. Vol. 255. pp. 133–76. doi:10.1016/S0074-7696(06)55003-X. ISBN 9780123735997. PMID 17178466.
  4. ^ Frank J, Schlichting I (September 2004). "Time-resolved imaging of macromolecular processes and interactions". Journal of Structural Biology. 147 (3): 209–10. doi:10.1016/j.jsb.2004.06.003. PMID 15450290.