Biomarker

For other uses, see Biomarker (disambiguation).

In biomedical contexts, a biomarker, or biological marker, is a measurable indicator of some biological state or condition. Biomarkers are often measured and evaluated using blood, urine, or soft tissues[1] to examine normal biological processes, pathogenic processes, or pharmacologic responses to a therapeutic intervention.[2] Biomarkers are used in many scientific fields.

  1. ^ Hirsch MS, Watkins J (May 2020). "A Comprehensive Review of Biomarker Use in the Gynecologic Tract Including Differential Diagnoses and Diagnostic Pitfalls". Advances in Anatomic Pathology. 27 (3): 164–192. doi:10.1097/PAP.0000000000000238. PMID 31149908. S2CID 171094630.
  2. ^ Biomarkers Definitions Working Group (March 2001). "Biomarkers and surrogate endpoints: preferred definitions and conceptual framework". Clinical Pharmacology and Therapeutics (Review). 69 (3): 89–95. doi:10.1067/mcp.2001.113989. PMID 11240971. S2CID 288484. as cited in Siderowf A, Aarsland D, Mollenhauer B, Goldman JG, Ravina B (April 2018). "Biomarkers for cognitive impairment in Lewy body disorders: Status and relevance for clinical trials". Movement Disorders (Review). 33 (4): 528–536. doi:10.1002/mds.27355. PMID 29624752. S2CID 4634411.