Blokhin (Russian: Блохин, Ukrainian: Блохін) might refer to one of the following:
- People
- Alexander Viktorovich Blokhin (born 1951), Russian diplomat
- Alexis Blokhina (born 2004), American tennis player
- Iryna Blokhina (born 1983), Ukrainian singer and poet, daughter of Oleh Blokhin
- Nikolai Blokhin [ru] (1912 - 1993), Soviet surgeon and oncologist
- Oleg Blokhin (born 1952), Soviet and Ukrainian football coach
- Oleh Olehovych Blokhin (born 1980), Ukrainian football player
- Sofia Blokhin (born 2006), Estonian chess player
- Tatyana Blokhina (born 1970), Russian heptathlete
- Vasili Blokhin (1895–1955), chief executioner during Stalin's purges
- Yevgeniy Blokhin (born 1979), Kazakh ice hockey player