Bolus (medicine)

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In medicine, a bolus (from Latin bolus, ball) is the administration of a discrete amount of medication, drug, or other compound within a specific time, generally 1–30 minutes,^[1] to raise its concentration in blood to an effective level. The administration can be given by injection: intravenously, intramuscularly, intrathecally, subcutaneously, or by inhalation.^{[clarification needed]} The article on routes of administration provides more information, as the preceding list of ROAs is not exhaustive.