Bone decalcification

Bone decalcification is the softening of bones due to the removal of calcium ions, and can be performed as a histological technique to study bones and extract DNA.[1][2] This process also occurs naturally during bone development and growth, and when uninhibited, can cause diseases such as osteomalacia.[3]

  1. ^ Howe, Percy (1922). "Decalcification of teeth and bones, and regeneration of bone through diet". Journal of the American Medical Association. 79 (19): 1565–1567. doi:10.1001/jama.1922.02640190003002.
  2. ^ Prasad, Donoghue (2013). "A comparative study of various decalcification techniques". Indian J Dent Res. 24 (3): 302–308. doi:10.4103/0970-9290.117991. PMID 24025875.
  3. ^ Hutchison, Florence (1992). "Osteomalacia and rickets". Seminars in Nephrology. 12 (2): 127–45. PMID 1561493.