Borrelia burgdorferi

Borrelia burgdorferi
Borrelia burgdorferi
Scientific classification Edit this classification
Domain: Bacteria
Phylum: Spirochaetota
Class: Spirochaetia
Order: Spirochaetales
Family: Borreliaceae
Genus: Borrelia
Species:
B. burgdorferi
Binomial name
Borrelia burgdorferi
Johnson et al. 1984 emend. Baranton et al. 1992

Borrelia burgdorferi is a gram-negative[1] bacterial species of the spirochete class in the genus Borrelia, and is one of the causative agents of Lyme disease in humans.[2][3] Along with a few similar genospecies, some of which also cause Lyme disease, it makes up the species complex of Borrelia burgdorferi sensu lato. The complex currently comprises 20 accepted and 3 proposed genospecies.[3] B. burgdorferi sensu stricto exists in North America and Eurasia and until 2016 was the only known cause of Lyme disease in North America.[4][5][3]

  1. ^ Samuels DS; Radolf, JD, eds. (2010). "Chapter 6, Structure, Function and Biogenesis of the Borrelia Cell Envelope". Borrelia: Molecular Biology, Host Interaction and Pathogenesis. Caister Academic Press. ISBN 978-1-904455-58-5.
  2. ^ Radolf JD, Samuels DS, eds. (2021). Lyme Disease and Relapsing Fever Spirochetes: Genomics, Molecular Biology, Host Interactions, and Disease Pathogenesis. Caister Academic Press. ISBN 978-1-913652-61-6.
  3. ^ a b c Wolcott, Katherine A.; Margos, Gabriele; Fingerle, Volker; Becker, Noémie S. (September 2021). "Host association of Borrelia burgdorferi sensu lato: A review". Ticks and Tick-borne Diseases. 12 (5): 101766. doi:10.1016/j.ttbdis.2021.101766. PMID 34161868.
  4. ^ CDC (2016-02-08). "New Lyme-disease-causing bacteria species discovered". Centers for Disease Control and Prevention. Retrieved 2019-01-18.
  5. ^ Tilly, Kit; Rosa, Patricia A.; Stewart, Philip E. (2008). "Biology of Infection with Borrelia burgdorferi". Infectious Disease Clinics of North America. 22 (2): 217–234. doi:10.1016/j.idc.2007.12.013. PMC 2440571. PMID 18452798.