| albumin | |||||||
|---|---|---|---|---|---|---|---|
 | |||||||
| Identifiers | |||||||
| Organism | |||||||
| Symbol | ALB | ||||||
| Entrez | 280717 | ||||||
| HomoloGene | 105925 | ||||||
| RefSeq (mRNA) | NM_180992 | ||||||
| RefSeq (Prot) | NP_851335 | ||||||
| UniProt | P02769 | ||||||
| Other data | |||||||
| Chromosome | 6: 91.54 - 91.57 Mb | ||||||
| |||||||
Bovine serum albumin (BSA or "Fraction V") is a serum albumin protein derived from cows. It is often used as a protein concentration standard in lab experiments.
The nickname "Fraction V" refers to albumin being the fifth fraction of the original Edwin Cohn purification methodology that made use of differential solubility characteristics of plasma proteins. By manipulating solvent concentrations, pH, salt levels, and temperature, Cohn was able to pull out successive "fractions" of blood plasma. The process was first commercialized with human albumin for medical use and later adopted for production of BSA.
