Bradykinin receptor B2

BDKRB2
Identifiers
Aliases	BDKRB2, B2R, BK-2, BK2, BKR2, BRB2, bradykinin receptor B2
External IDs	OMIM: 113503; MGI: 102845; HomoloGene: 519; GeneCards: BDKRB2; OMA:BDKRB2 - orthologs
Gene location (Human)
Chr.	Chromosome 14 (human)
End	96,244,166 bp
Gene location (Mouse)
Chr.	Chromosome 12 (mouse)
End	105,561,496 bp
RNA expression pattern
	Top expressed in
	stromal cell of endometrium; ; mucosa of urinary bladder; ; pancreatic ductal cell; ; tendon of biceps brachii; ; gums; ; cartilage tissue; ; gingival epithelium; ; gallbladder; ; ectocervix; ; canal of the cervix;
	Top expressed in
	esophagus; ; embryo; ; embryo; ; adrenal gland; ; pituitary gland; ; lip; ; duodenum; ; placenta; ; muscle of thigh; ; ileum;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	G protein-coupled receptor activity; type 1 angiotensin receptor binding; signal transducer activity; protease binding; protein binding; protein heterodimerization activity; phosphatidylinositol phospholipase C activity; bradykinin receptor activity;
Cellular component	integral component of membrane; endosome; membrane; integral component of plasma membrane; plasma membrane;
Biological process	G protein-coupled receptor signaling pathway; negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress; response to salt stress; vasoconstriction; transmembrane receptor protein tyrosine kinase signaling pathway; response to stress; negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator; vasodilation; blood circulation; cell surface receptor signaling pathway; regulation of vascular permeability; regulation of vasoconstriction; negative regulation of peptidyl-serine phosphorylation; inflammatory response; arachidonic acid secretion; signal transduction; smooth muscle contraction; positive regulation of cytosolic calcium ion concentration;
	Sources:Amigo / QuickGO
Orthologs
	624
	12062
	ENSG00000168398
	ENSMUSG00000021070
	P30411
	P32299
	NM_000623; NM_001379692
	NM_009747
	NP_000614; NP_001366621
	NP_033877
	Wikidata
View/Edit Human	View/Edit Mouse

Bradykinin receptor B₂ is a G-protein coupled receptor for bradykinin, encoded by the BDKRB2 gene in humans.

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000168398 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000021070 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000168398 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000021070 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

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