Brain atlas

A brain atlas is composed of serial sections along different anatomical planes of the healthy or diseased developing or adult animal or human brain where each relevant brain structure is assigned a number of coordinates to define its outline or volume. Brain atlases are contiguous, comprehensive results of visual brain mapping and may include anatomical, genetic or functional features.[1] A functional brain atlas is made up of regions of interest, where these regions are typically defined as spatially contiguous and functionally coherent patches of gray matter.[2]

In most atlases, the three dimensions are: latero-lateral (x), dorso-ventral (y) and rostro-caudal (z). The possible sections are

Surface maps are sometimes used in addition to the 3D serial section maps[3]

Besides the human brain,[4] brain atlases exist for the brains of the mouse,[5] rhesus macaques,[6] Drosophila,[7] pig[8] and others.

Notable examples include the Allen Brain Atlas, BrainMaps, BigBrain, Infant Brain Atlas,[9] and the work of the International Consortium for Brain Mapping (ICBM).

  1. ^ Beliveau, Vincent; Ganz, Melanie; Feng, Ling; Ozenne, Brice; Højgaard, Liselotte; Fisher, Patrick M.; Svarer, Claus; Greve, Douglas N.; Knudsen, Gitte M. (2017-01-04). "A High-Resolution In Vivo Atlas of the Human Brain's Serotonin System". Journal of Neuroscience. 37 (1): 120–128. doi:10.1523/jneurosci.2830-16.2016. PMC 5214625. PMID 28053035.
  2. ^ Varoquaux, Gaël; Craddock, R. Cameron (October 2013). "Learning and comparing functional connectomes across subjects". NeuroImage. 80: 405–415. arXiv:1304.3880. doi:10.1016/j.neuroimage.2013.04.007. PMID 23583357. S2CID 5956612.
  3. ^ "NeuroMaps Tools". Thehumanbrain.info. Retrieved 2023-03-11.
  4. ^ "The Human Brain · Atlas of the Human Brain · www.thehumanbrain.info · Homepage". Thehumanbrain.info. Retrieved 2016-01-30.
  5. ^ "ISH Data :: Allen Brain Atlas: Mouse Brain". Mouse.brain-map.org. Retrieved 2016-01-30.
  6. ^ "Home :: NIH Blueprint Non-Human Primate (NHP) Atlas". Blueprintnhpatlas.org. Retrieved 2016-01-30.
  7. ^ "Flybrain Front Page". Flybrain.neurobio.arizona.edu. 2000-07-26. Archived from the original on 1998-01-09. Retrieved 2016-01-30.
  8. ^ Villadsen, Jonas; Hansen, Hanne D.; Jørgensen, Louise M.; Keller, Sune H.; Andersen, Flemming L.; Petersen, Ida N.; Knudsen, Gitte M.; Svarer, Claus (2018). "Automatic delineation of brain regions on MRI and PET images from the pig". Journal of Neuroscience Methods. 294: 51–58. doi:10.1016/j.jneumeth.2017.11.008. PMID 29146191. S2CID 38308791.
  9. ^ Ahmad S, Wu W, Wu Z, Thung KH, Liu S, Lin W, Li G, Wang L, Yap PT (2023). "Multifaceted atlases of the human brain in its infancy". Nature Methods. 20 (1): 55–64. doi:10.1038/s41592-022-01703-z. PMC 9834057. PMID 36585454. S2CID 247600108.