Brandon Smith may refer to:
- Brandon Alan Smith, American actor, stunt double and stunt coordinator
- Brandon Smith (actor) (1952−2023), American actor
- Brandon Smith (teacher), member of BCHS
- Brandon Smith (ice hockey) (born 1973), Canadian ice hockey player
- Brandon Smith (defensive back, born 1984) (born 1984), Canadian football player
- Brandon Smith (defensive back, born 1987) (born 1987), American football cornerback
- Brandon Smith (linebacker) (born 2001), American football linebacker
- Brandon Smith (rugby league) (born 1996), New Zealand rugby league player
- Brandon Mychal Smith (born 1989), American actor
- Brandon Smith, Los Angeles based musician, producer and the creator of The Anix, former member of Apoptygma Berzerk