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Routes of administration | Oral |
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Protein binding | 98% |
Elimination half-life | 9-14 hours |
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Chemical and physical data | |
Formula | C14H16BrNO2 |
Molar mass | 310.191 g·mol−1 |
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Brofaromine (proposed brand name Consonar) is a reversible inhibitor of monoamine oxidase A (RIMA) discovered by Ciba-Geigy.[1] The compound was primarily researched in the treatment of depression and anxiety but its development was dropped before it was brought to market.[2]
Brofaromine also acts as a serotonin reuptake inhibitor, and its dual pharmacologic effects offered promise in the treatment of a wide spectrum of depressed patients while producing less severe anticholinergic side effects in comparison with older standard drugs like certain of the tricyclic antidepressants.