Bromoform

Bromoform
Skeletal formula of bromoform
Skeletal formula of bromoform
Stereo, skeletal formula of bromoform with the explicit hydrogen added
Stereo, skeletal formula of bromoform with the explicit hydrogen added
Spacefill model of bromoform

A bottle of bromoform with some in the adjacent beaker
Names
Preferred IUPAC name
Tribromomethane[1]
Other names
Identifiers
3D model (JSmol)
Abbreviations
1731048
ChEBI
ChEMBL
ChemSpider
DrugBank
ECHA InfoCard 100.000.777 Edit this at Wikidata
EC Number
  • 200-854-6
49500
KEGG
MeSH bromoform
RTECS number
  • PB5600000
UNII
UN number 2515
  • InChI=1S/CHBr3/c2-1(3)4/h1H checkY
    Key: DIKBFYAXUHHXCS-UHFFFAOYSA-N checkY
  • BrC(Br)Br
Properties
CHBr3
Molar mass 252.731 g·mol−1
Appearance Colorless liquid
Density 2.89 g/cm3
Melting point 8.69 °C; 47.64 °F; 281.84 K
Boiling point 149.40 °C; 300.92 °F; 422.55 K
3.2 g L−1 (at 30 °C)
log P 2.435
Vapor pressure 670 Pa (at 20.0 °C)
17 μmol Pa−1 kg−1
Acidity (pKa) 13.7
-82.60·10−6 cm3/mol
1.595
Thermochemistry
130.5 J K−1 mol−1
6.1–12.7 kJ mol−1
−549.1–−542.5 kJ mol−1
Hazards
GHS labelling:
GHS06: Toxic GHS09: Environmental hazard
Danger
H302, H315, H319, H331, H411
P261, P273, P305+P351+P338, P311
NFPA 704 (fire diamond)
NFPA 704 four-colored diamondHealth 3: Short exposure could cause serious temporary or residual injury. E.g. chlorine gasFlammability 0: Will not burn. E.g. waterInstability 0: Normally stable, even under fire exposure conditions, and is not reactive with water. E.g. liquid nitrogenSpecial hazards (white): no code
3
0
0
Lethal dose or concentration (LD, LC):
933.0 mg kg−1 (oral, rat)
1400 mg/kg (mouse, oral)
1147 mg/kg (rat, oral)[4]
1151 ppm (mammal)[4]
4282 ppm (rat, 4 hr)
7000 ppm (dog, 1 hr)[4]
NIOSH (US health exposure limits):
PEL (Permissible)
 TWA 0.5 ppm (5 mg/m3) [skin][2]
REL (Recommended)
 TWA 0.5 ppm (5 mg/m3) [skin][2]
IDLH (Immediate danger)
 850 ppm[2]
Related compounds
Related alkanes
Supplementary data page
Bromoform (data page)
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Bromoform is an organic compound with the chemical formula CHBr3. It is a colorless liquid at room temperature, with a high refractive index and a very high density. Its sweet odor is similar to that of chloroform. It is one of the four haloforms, the others being fluoroform, chloroform, and iodoform. It is a brominated organic solvent. Currently its main use is as a laboratory reagent. It is very slightly soluble in water (one part bromoform in 800 parts water) and is miscible with alcohol, benzene, chloroform, ether, petroleum ether, acetone and oils.

  1. ^ a b Nomenclature of Organic Chemistry : IUPAC Recommendations and Preferred Names 2013 (Blue Book). Cambridge: The Royal Society of Chemistry. 2014. p. 661. doi:10.1039/9781849733069-FP001. ISBN 978-0-85404-182-4. The retained names 'bromoform' for HCBr3, 'chloroform' for HCCl3, and 'iodoform' for HCI3 are acceptable in general nomenclature. Preferred IUPAC names are substitutive names.
  2. ^ a b c d NIOSH Pocket Guide to Chemical Hazards. "#0066". National Institute for Occupational Safety and Health (NIOSH).
  3. ^ Rumble, John (18 June 2018). CRC Handbook of Chemistry and Physics. CRC Press. pp. 3–50. ISBN 9781138561632.
  4. ^ a b c "Bromoform". Immediately Dangerous to Life or Health Concentrations (IDLH). National Institute for Occupational Safety and Health (NIOSH).