Buparvaquone

Buparvaquone
Clinical data
ATCvet code	QP51EX03 (WHO) ;
Identifiers
	IUPAC name 2-((4-tert-butylcyclohexyl)methyl)-3-hydroxy-1,4-naphthoquinone;
CAS Number	88426-33-9 ;
ChemSpider	10807457 ;
UNII	0354RT7LG4;
ChEMBL	ChEMBL292009 ;
CompTox Dashboard (EPA)	DTXSID4057849 ;
ECHA InfoCard	100.115.556
Chemical and physical data
Formula	C21H26O3
Molar mass	326.436 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES CC(C)(C)C3CCC(C\C2=C(/O)C(=O)c1ccccc1C2=O)CC3;
	InChI InChI=1S/C21H26O3/c1-21(2,3)14-10-8-13(9-11-14)12-17-18(22)15-6-4-5-7-16(15)19(23)20(17)24/h4-7,13-14,24H,8-12H2,1-3H3 ; Key:KLLIVCPQDTYMLC-UHFFFAOYSA-N ;
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Buparvaquone is a naphthoquinone antiprotozoal drug related to atovaquone. It is a promising compound for the therapy and prophylaxis of all forms of theileriosis. Buparvaquone has been shown to have anti-leishmanial activity in vitro. It can be used to treat bovine East Coast fever protozoa in vitro, along with the only other substance known – Peganum harmala.^{[citation needed]} It is the only really effective commercial therapeutic product against bovine theileriosis, where it has been used since the late 1980s.^{[citation needed]}

Clinical data

ATCvet code	QP51EX03 (WHO)
Identifiers
IUPAC name 2-((4-tert-butylcyclohexyl)methyl)-3-hydroxy-1,4-naphthoquinone
CAS Number	88426-33-9^N
ChemSpider	10807457^Y
UNII	0354RT7LG4
ChEMBL	ChEMBL292009^N
CompTox Dashboard (EPA)	DTXSID4057849
ECHA InfoCard	100.115.556
Chemical and physical data
Formula	C₂₁H₂₆O₃
Molar mass	326.436 g·mol⁻¹
3D model (JSmol)	Interactive image
SMILES CC(C)(C)C3CCC(C\C2=C(/O)C(=O)c1ccccc1C2=O)CC3
InChI InChI=1S/C21H26O3/c1-21(2,3)14-10-8-13(9-11-14)12-17-18(22)15-6-4-5-7-16(15)19(23)20(17)24/h4-7,13-14,24H,8-12H2,1-3H3^Y Key:KLLIVCPQDTYMLC-UHFFFAOYSA-N^Y
^NY (what is this?) (verify)