Butenafine

Butenafine
Clinical data
Trade namesMentax, Lotrimin Ultra
AHFS/Drugs.comMonograph
Routes of
administration
Topical (cream)
ATC code
Legal status
Legal status
  • OTC (Lotrimin Ultra), Rx-only (Mentax)
Pharmacokinetic data
MetabolismHepatic
Elimination half-life35–100 hours
Identifiers
  • [(4-tert-butylphenyl)methyl](methyl)(naphthalen-1-ylmethyl)amine
CAS Number
PubChem CID
DrugBank
ChemSpider
UNII
KEGG
ChEBI
ChEMBL
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC23H27N
Molar mass317.476 g·mol−1
3D model (JSmol)
  • N(C)(Cc1ccc(cc1)C(C)(C)C)Cc3c2ccccc2ccc3
  • InChI=1S/C23H27N/c1-23(2,3)21-14-12-18(13-15-21)16-24(4)17-20-10-7-9-19-8-5-6-11-22(19)20/h5-15H,16-17H2,1-4H3 checkY
  • Key:ABJKWBDEJIDSJZ-UHFFFAOYSA-N checkY
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Butenafine, sold under the brand names Lotrimin Ultra, Mentax, and Butop (In India only), is a synthetic benzylamine derived antifungal drug.

It is structurally related to the allylamine antifungals terbinafine & naftifine.

  1. ^ Mylan Pharmaceuticals Inc. "Mentax (butenafine hydrochloride) Cream. Human Prescription Drug Label". dailymed.nlm.nih.gov. National Institutes of Health, U.S. National Library of Medicine, Health & Human Services. Retrieved 24 August 2016.