CA10

CA10
Identifiers
Aliases	CA10, CA-RPX, CARPX, HUCEP-15, carbonic anhydrase 10
External IDs	OMIM: 604642; MGI: 1919855; HomoloGene: 23201; GeneCards: CA10; OMA:CA10 - orthologs
Gene location (Human)
Chr.	Chromosome 17 (human)
End	52,160,017 bp
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)
End	93,492,575 bp
RNA expression pattern
	Top expressed in
	cerebellar cortex; ; cerebellar hemisphere; ; right hemisphere of cerebellum; ; cerebellar vermis; ; middle temporal gyrus; ; prefrontal cortex; ; dorsolateral prefrontal cortex; ; pons; ; right frontal lobe; ; Brodmann area 23;
	Top expressed in
	lobe of cerebellum; ; cerebellar vermis; ; primary motor cortex; ; habenula; ; ventromedial nucleus; ; anterior amygdaloid area; ; Epithelium of choroid plexus; ; cingulate gyrus; ; prefrontal cortex; ; piriform cortex;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	molecular function; carbonate dehydratase activity; zinc ion binding; carbonic anhydrase;
Cellular component	cellular component;
Biological process	brain development;
	Sources:Amigo / QuickGO
Orthologs
	56934
	72605
	ENSG00000154975
	ENSMUSG00000056158
	Q9NS85
	P61215
	NM_001082533; NM_001082534; NM_020178
	NM_028296; NM_001361707; NM_001361708
	NP_001076002; NP_001076003; NP_064563
	NP_082572; NP_001348636; NP_001348637
	Wikidata
View/Edit Human	View/Edit Mouse

Carbonic anhydrase-related protein 10 is an enzyme that in humans is encoded by the CA10 gene.^[5]^[6]^[7]

This gene encodes a protein that belongs to the carbonic anhydrase family of zinc metalloenzymes, which catalyze the reversible hydration of carbon dioxide in various biological processes. The protein encoded by this gene is an acatalytic member of the alpha-carbonic anhydrase subgroup, and it is thought to play a role in the central nervous system, especially in brain development. Multiple transcript variants encoding the same protein have been found for this gene.^[7]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000154975 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000056158 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Hewett-Emmett D, Tashian RE (Aug 1996). "Functional diversity, conservation, and convergence in the evolution of the alpha-, beta-, and gamma-carbonic anhydrase gene families". Mol Phylogenet Evol. 5 (1): 50–77. doi:10.1006/mpev.1996.0006. PMID 8673298.
^ Kleiderlein JJ, Nisson PE, Jessee J, Li WB, Becker KG, Derby ML, Ross CA, Margolis RL (Feb 1999). "CCG repeats in cDNAs from human brain". Hum Genet. 103 (6): 666–73. doi:10.1007/s004390050889. PMID 9921901. S2CID 23696667.
^ ^a ^b "Entrez Gene: CA10 carbonic anhydrase X".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000154975 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000056158 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid8673298-5] Hewett-Emmett D, Tashian RE (Aug 1996). "Functional diversity, conservation, and convergence in the evolution of the alpha-, beta-, and gamma-carbonic anhydrase gene families". Mol Phylogenet Evol. 5 (1): 50–77. doi:10.1006/mpev.1996.0006. PMID 8673298.

[pmid9921901-6] Kleiderlein JJ, Nisson PE, Jessee J, Li WB, Becker KG, Derby ML, Ross CA, Margolis RL (Feb 1999). "CCG repeats in cDNAs from human brain". Hum Genet. 103 (6): 666–73. doi:10.1007/s004390050889. PMID 9921901. S2CID 23696667.

[entrez-7] "Entrez Gene: CA10 carbonic anhydrase X".

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