CACNG2

CACNG2
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	3JXT
Identifiers
Aliases	CACNG2, MRD10, calcium voltage-gated channel auxiliary subunit gamma 2
External IDs	OMIM: 602911; MGI: 1316660; HomoloGene: 4432; GeneCards: CACNG2; OMA:CACNG2 - orthologs
Gene location (Human)
Chr.	Chromosome 22 (human)
End	36,703,752 bp
Gene location (Mouse)
Chr.	Chromosome 15 (mouse)
End	78,004,228 bp
RNA expression pattern
	Top expressed in
	right hemisphere of cerebellum; ; postcentral gyrus; ; Brodmann area 46; ; superior frontal gyrus; ; prefrontal cortex; ; right frontal lobe; ; dorsolateral prefrontal cortex; ; entorhinal cortex; ; Brodmann area 9; ; anterior cingulate cortex;
	Top expressed in
	anterior horn of spinal cord; ; lumbar subsegment of spinal cord; ; cerebellar vermis; ; lobe of cerebellum; ; medulla oblongata; ; medial dorsal nucleus; ; primary motor cortex; ; medial vestibular nucleus; ; facial motor nucleus; ; medial geniculate nucleus;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	voltage-gated ion channel activity; protein binding; channel regulator activity; calcium channel activity; voltage-gated calcium channel activity; ionotropic glutamate receptor binding;
Cellular component	voltage-gated calcium channel complex; integral component of membrane; endocytic vesicle membrane; membrane; plasma membrane; AMPA glutamate receptor complex; cell junction; neuron projection; synapse; postsynaptic density membrane; somatodendritic compartment; cytosol; cell surface; postsynaptic density; cerebellar mossy fiber; Schaffer collateral - CA1 synapse; hippocampal mossy fiber to CA3 synapse; glutamatergic synapse; integral component of postsynaptic density membrane;
Biological process	membrane hyperpolarization; transmission of nerve impulse; regulation of membrane potential; regulation of ion transmembrane transport; membrane depolarization; nervous system process; ion transport; regulation of AMPA receptor activity; neuromuscular junction development; calcium ion transport; calcium ion transmembrane transport; neurotransmitter receptor transport, postsynaptic endosome to lysosome; postsynaptic neurotransmitter receptor diffusion trapping; neurotransmitter receptor internalization; protein targeting to membrane; response to calcium ion; eye blink reflex; positive regulation of protein localization to basolateral plasma membrane; positive regulation of AMPA receptor activity; regulation of postsynaptic membrane neurotransmitter receptor levels; neurotransmitter receptor localization to postsynaptic specialization membrane; positive regulation of synaptic transmission, glutamatergic; cardiac conduction;
	Sources:Amigo / QuickGO
Orthologs
	10369
	12300
	ENSG00000166862
	ENSMUSG00000019146
	Q9Y698
	O88602
	NM_006078; NM_001379051
	NM_007583
	NP_006069; NP_001365980
	NP_031609
	Wikidata
View/Edit Human	View/Edit Mouse

Calcium channel, voltage-dependent, gamma subunit 2, also known as CACNG2 or stargazin is a protein that in humans is encoded by the CACNG2 gene.^[5]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000166862 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000019146 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: CACNG2 calcium channel, voltage-dependent, gamma subunit 2".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000166862 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000019146 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Entrez Gene: CACNG2 calcium channel, voltage-dependent, gamma subunit 2".

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