CATH database

CATH
Content
DescriptionProtein Structure Classification
Contact
Research centerUniversity College London
LaboratoryInstitute of Structural and Molecular Biology
Primary citationDawson et al. (2016) [1]
Release date1997
Access
Websitecathdb.info
Download URLcathdb.info/download
Miscellaneous
Data release
frequency
CATH-B is released daily. Official releases are approximately annual.
Version4.3
Schematic representation of the three top levels of the CATH classification scheme.[2]

The CATH Protein Structure Classification database is a free, publicly available online resource that provides information on the evolutionary relationships of protein domains. It was created in the mid-1990s by Professor Christine Orengo and colleagues including Janet Thornton and David Jones,[2] and continues to be developed by the Orengo group at University College London. CATH shares many broad features with the SCOP resource, however there are also many areas in which the detailed classification differs greatly.[3][4][5][6]

  1. ^ Dawson NL, Lewis TE, Das S, Lees JG, Lee D, Ashford P, et al. (January 2017). "CATH: an expanded resource to predict protein function through structure and sequence". Nucleic Acids Research. 45 (D1): D289–D295. doi:10.1093/nar/gkw1098. PMC 5210570. PMID 27899584.
  2. ^ a b Orengo CA, Michie AD, Jones S, Jones DT, Swindells MB, Thornton JM (August 1997). "CATH--a hierarchic classification of protein domain structures". Structure. 5 (8). London, England: 1093–108. doi:10.1016/s0969-2126(97)00260-8. PMID 9309224.
  3. ^ "CATH: Protein Structure Classification Database at UCL". Cathdb.info. Retrieved 9 March 2017.
  4. ^ "CATH". Cathdb.info. Retrieved 9 March 2017.
  5. ^ "CATH Database (@CATHDatabase)". Twitter. Retrieved 9 March 2017.
  6. ^ Pearl FM, Bennett CF, Bray JE, Harrison AP, Martin N, Shepherd A, et al. (January 2003). "The CATH database: an extended protein family resource for structural and functional genomics". Nucleic Acids Research. 31 (1): 452–455. doi:10.1093/nar/gkg062. PMC 165509. PMID 12520050.