CCDC78

CCDC78
Identifiers
Aliases	CCDC78, C16orf25, CNM4, JFP10, hsCcdc78, coiled-coil domain containing 78
External IDs	OMIM: 614666; MGI: 2685784; HomoloGene: 105408; GeneCards: CCDC78; OMA:CCDC78 - orthologs
Gene location (Human)
Chr.	Chromosome 16 (human)
End	726,954 bp
Gene location (Mouse)
Chr.	Chromosome 17 (mouse)
End	26,009,487 bp
RNA expression pattern
	Top expressed in
	right uterine tube; ; bronchial epithelial cell; ; olfactory zone of nasal mucosa; ; nasal epithelium; ; mucosa of paranasal sinus; ; right hemisphere of cerebellum; ; caudate nucleus; ; putamen; ; nucleus accumbens; ; pituitary gland;
	Top expressed in
	ovary; ; hypothalamus; ; lung; ; embryo; ; spermatocyte; ; morula; ; bone marrow; ; lens; ; cerebellum; ; cerebellar cortex;
	More reference expression data
	n/a
Orthologs
	124093
	381077
	ENSG00000162004
	ENSMUSG00000071202
	A2IDD5
	D3Z5T1
	NM_001031737; NM_173476; NM_001378030; NM_001378031; NM_001378033
	NM_001165929
	NP_001026907; NP_001364959; NP_001364960; NP_001364962
	NP_001159401
	Wikidata
View/Edit Human	View/Edit Mouse

Coiled-coil domain-containing 78 (CCDC78) is a protein in humans encoded by the CCDC78 gene. It has several aliases including C16orf25, FLJ34512, CNM4, and JFP10.^[5] It is located on the (-) strand on chromosome 16 (16p13.3). Its gene neighborhood includes NARFL (also on the minus strand), HAGHL, FAM173A, and METRN. The CCDC78 gene is 10,892 base pairs long, and the protein contains 438 amino acids.^[6] The protein weighs approximately 4.852 KDal.^[7] There are several isoforms, including one indicated with a unique congenital myopathy.^[8] Several expression profiles show it has ubiquitous expression at moderate levels. Although no paralogs exist several orthologs do.

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000162004 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000071202 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ GeneCards. "CCDC78 Gene". The Human Gene Compendium. Retrieved 2 May 2013.
^ "CCDC78". National Center for Biotechnology Information.
^ Biology WorkBench. San Diego Supercomputer Center http://seqtool.sdsc.edu/CGI/BW.cgi#!. {{cite web}}: Missing or empty |title= (help)^{[permanent dead link]}
^ Cite error: The named reference Majczenko et al. was invoked but never defined (see the help page).

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000162004 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000071202 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[GeneCards-5] GeneCards. "CCDC78 Gene". The Human Gene Compendium. Retrieved 2 May 2013.

[NCBI-6] "CCDC78". National Center for Biotechnology Information.

[BiologyWorkBench-7] Biology WorkBench. San Diego Supercomputer Center http://seqtool.sdsc.edu/CGI/BW.cgi#!. {{cite web}}: Missing or empty |title= (help)^{[permanent dead link]}

[Majczenko_et_al.-8] Cite error: The named reference Majczenko et al. was invoked but never defined (see the help page).

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