CD46

CD46
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesCD46, AHUS2, MCP, MIC10, TLX, TRA2.10, CD46 molecule
External IDsOMIM: 120920; MGI: 1203290; HomoloGene: 7832; GeneCards: CD46; OMA:CD46 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_010778

RefSeq (protein)

NP_034908

Location (UCSC)Chr 1: 207.75 – 207.8 MbChr 1: 194.72 – 194.77 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

CD46 complement regulatory protein also known as CD46 (cluster of differentiation 46) and Membrane Cofactor Protein is a protein which in humans is encoded by the CD46 gene.[5] CD46 is an inhibitory complement receptor.[6]

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000117335Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000016493Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Taylor CT, Biljan MM, Kingsland CR, Johnson PM (May 1994). "Inhibition of human spermatozoon-oocyte interaction in vitro by monoclonal antibodies to CD46 (membrane cofactor protein)". Hum. Reprod. 9 (5): 907–11. doi:10.1093/oxfordjournals.humrep.a138615. PMID 7929741.
  6. ^ Liszewski MK, Post TW, Atkinson JP (1991). "Membrane cofactor protein (MCP or CD46): newest member of the regulators of complement activation gene cluster". Annu. Rev. Immunol. 9 (1): 431–55. doi:10.1146/annurev.iy.09.040191.002243. PMID 1910685.