CELA3B

CELA3B
Identifiers
AliasesCELA3B, CBPP, E1, EL-1, ELA3B, chymotrypsin like elastase family member 3B, chymotrypsin like elastase 3B
External IDsMGI: 1915118; HomoloGene: 128227; GeneCards: CELA3B; OMA:CELA3B - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_007352

NM_026419

RefSeq (protein)

NP_031378

NP_080695

Location (UCSC)Chr 1: 21.98 – 22 MbChr 4: 137.15 – 137.16 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Chymotrypsin-like elastase family member 3B also known as elastase-3B, protease E, or fecal elastase is an enzyme that in humans is encoded by the CELA3B gene.[5][6][7]

Clinical literature that describes human elastase 1 activity in the pancreas or fecal material is actually referring to chymotrypsin-like elastase family member 3B (i.e. the enzyme / protein this article focuses on).[8]

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000219073Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000023433Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Tani T, Ohsumi J, Mita K, Takiguchi Y (Feb 1988). "Identification of a novel class of elastase isozyme, human pancreatic elastase III, by cDNA and genomic gene cloning". J Biol Chem. 263 (3): 1231–9. doi:10.1016/S0021-9258(19)57291-X. PMID 2826474.
  6. ^ Shirasu Y, Takemura K, Yoshida H, Sato Y, Iijima H, Shimada Y, Mikayama T, Ozawa T, Ikeda N, Ishida A, et al. (Dec 1988). "Molecular cloning of complementary DNA encoding one of the human pancreatic protease E isozymes". J Biochem. 104 (2): 259–64. doi:10.1093/oxfordjournals.jbchem.a122454. PMID 2460440.
  7. ^ "Entrez Gene: ELA3B elastase 3B, pancreatic".
  8. ^ "Entrez Gene: chymotrypsin-like elastase family, member 1".