CHD2

CHD2
Identifiers
Aliases	CHD2, EEOC, chromodomain helicase DNA binding protein 2, DEE94
External IDs	OMIM: 602119; MGI: 2448567; HomoloGene: 37462; GeneCards: CHD2; OMA:CHD2 - orthologs
Gene location (Human)
Chr.	Chromosome 15 (human)
End	93,027,996 bp
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)
End	73,191,578 bp
RNA expression pattern
	Top expressed in
	Achilles tendon; ; sural nerve; ; epithelium of colon; ; ventricular zone; ; ganglionic eminence; ; gastric mucosa; ; cerebellar hemisphere; ; right uterine tube; ; left ovary; ; left lobe of thyroid gland;
	Top expressed in
	otic vesicle; ; otolith organ; ; utricle; ; genital tubercle; ; Rostral migratory stream; ; hand; ; tail of embryo; ; mesenteric lymph nodes; ; ventricular zone; ; neural layer of retina;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	DNA binding; nucleotide binding; helicase activity; DNA helicase activity; histone binding; core promoter sequence-specific DNA binding; protein binding; hydrolase activity; ATP binding; RNA binding; RNA polymerase II cis-regulatory region sequence-specific DNA binding;
Cellular component	intracellular membrane-bounded organelle; nucleoplasm; nucleolus; extracellular exosome; nucleus;
Biological process	regulation of transcription, DNA-templated; regulation of transcription by RNA polymerase II; muscle organ development; transcription, DNA-templated; cellular response to DNA damage stimulus; hematopoietic stem cell differentiation; DNA duplex unwinding; chromatin organization;
	Sources:Amigo / QuickGO
Orthologs
	1106
	244059
	ENSG00000173575
	ENSMUSG00000078671
	O14647
	E9PZM4
	NM_001271; NM_001042572
	NM_001081345
	NP_001036037; NP_001262
	NP_001074814
	Wikidata
View/Edit Human	View/Edit Mouse

Chromodomain-helicase-DNA-binding protein 2 is an enzyme that in humans is encoded by the CHD2 gene.^[5]^[6]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000173575 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000078671 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Woodage T, Basrai MA, Baxevanis AD, Hieter P, Collins FS (Oct 1997). "Characterization of the CHD family of proteins". Proceedings of the National Academy of Sciences of the United States of America. 94 (21): 11472–7. Bibcode:1997PNAS...9411472W. doi:10.1073/pnas.94.21.11472. PMC 23509. PMID 9326634.
^ "Entrez Gene: CHD2 chromodomain helicase DNA binding protein 2".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000173575 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000078671 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid9326634-5] Woodage T, Basrai MA, Baxevanis AD, Hieter P, Collins FS (Oct 1997). "Characterization of the CHD family of proteins". Proceedings of the National Academy of Sciences of the United States of America. 94 (21): 11472–7. Bibcode:1997PNAS...9411472W. doi:10.1073/pnas.94.21.11472. PMC 23509. PMID 9326634.

[entrez-6] "Entrez Gene: CHD2 chromodomain helicase DNA binding protein 2".

[1]

[2]

[3]

[4]

[5]

[6]