CHRNA3

CHRNA3
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesCHRNA3, LNCR2, NACHRA3, PAOD2, cholinergic receptor nicotinic alpha 3 subunit, BAIPRCK
External IDsOMIM: 118503; MGI: 87887; HomoloGene: 591; GeneCards: CHRNA3; OMA:CHRNA3 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_000743
NM_001166694

NM_145129

RefSeq (protein)

NP_000734
NP_001160166

NP_660111

Location (UCSC)Chr 15: 78.59 – 78.62 MbChr 9: 54.92 – 54.93 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Neuronal acetylcholine receptor subunit alpha-3, also known as nAChRα3, is a protein that in humans is encoded by the CHRNA3 gene.[5][6] The protein encoded by this gene is a subunit of certain nicotinic acetylcholine receptors (nAchR). Research with mecamylamine in animals has implicated alpha-3-containing nAChRs in the abusive and addictive properties of ethanol.

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000080644Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000032303Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Eng CM, Kozak CA, Beaudet AL, Zoghbi HY (Apr 1991). "Mapping of multiple subunits of the neuronal nicotinic acetylcholine receptor to chromosome 15 in man and chromosome 9 in mouse". Genomics. 9 (2): 278–82. doi:10.1016/0888-7543(91)90253-B. PMID 2004777.
  6. ^ "Entrez Gene: CHRNA3 cholinergic receptor, nicotinic, alpha 3".