CHST4

CHST4
Identifiers
Aliases	CHST4, GST3, GlcNAc6ST2, HECGLCNAC6ST, LSST, carbohydrate sulfotransferase 4
External IDs	MGI: 1349479; HomoloGene: 4216; GeneCards: CHST4; OMA:CHST4 - orthologs
Gene location (Human)
Chr.	Chromosome 16 (human)
End	71,538,748 bp
Gene location (Mouse)
Chr.	Chromosome 8 (mouse)
End	110,766,372 bp
RNA expression pattern
	Top expressed in
	gallbladder; ; pancreatic ductal cell; ; testicle; ; islet of Langerhans; ; mucosa of ileum; ; body of pancreas; ; epithelium of bronchus; ; secondary oocyte; ; nasal epithelium; ; bronchial epithelial cell;
	Top expressed in
	colon; ; left colon; ; duodenum; ; morula; ; urethra; ; jejunum; ; ileum; ; epithelium of stomach; ; intestinal villus; ; secondary oocyte;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	transferase activity; sulfotransferase activity; N-acetylglucosamine 6-O-sulfotransferase activity;
Cellular component	integral component of membrane; Golgi apparatus; intrinsic component of Golgi membrane; membrane; Golgi membrane; trans-Golgi network;
Biological process	cell-cell signaling; cell adhesion; immune response; O-glycan processing; sulfur compound metabolic process; protein sulfation; inflammatory response; N-acetylglucosamine metabolic process; keratan sulfate biosynthetic process; carbohydrate metabolic process;
	Sources:Amigo / QuickGO
Orthologs
	10164
	26887
	ENSG00000140835
	ENSMUSG00000035930
	Q8NCG5
	Q9R1I1
	NM_005769; NM_001166395
	NM_011998
	NP_001159867; NP_005760
	NP_036128
	Wikidata
View/Edit Human	View/Edit Mouse

Carbohydrate sulfotransferase 4 is an enzyme that in humans is encoded by the CHST4 gene.^[5]^[6]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000140835 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000035930 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Bistrup A, Bhakta S, Lee JK, Belov YY, Gunn MD, Zuo FR, Huang CC, Kannagi R, Rosen SD, Hemmerich S (Jul 1999). "Sulfotransferases of Two Specificities Function in the Reconstitution of High Endothelial Cell Ligands for L-selectin". J Cell Biol. 145 (4): 899–910. doi:10.1083/jcb.145.4.899. PMC 2133194. PMID 10330415.
^ "Entrez Gene: CHST4 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000140835 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000035930 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid10330415-5] Bistrup A, Bhakta S, Lee JK, Belov YY, Gunn MD, Zuo FR, Huang CC, Kannagi R, Rosen SD, Hemmerich S (Jul 1999). "Sulfotransferases of Two Specificities Function in the Reconstitution of High Endothelial Cell Ligands for L-selectin". J Cell Biol. 145 (4): 899–910. doi:10.1083/jcb.145.4.899. PMC 2133194. PMID 10330415.

[entrez-6] "Entrez Gene: CHST4 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4".

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