CKM (gene)

CKM
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1I0E
Identifiers
Aliases	CKM, CKMM, M-CK, creatine kinase, M-type, CPK-M
External IDs	OMIM: 123310; MGI: 88413; HomoloGene: 20432; GeneCards: CKM; OMA:CKM - orthologs
Gene location (Human)
Chr.	Chromosome 19 (human)
End	45,322,875 bp
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)
End	19,156,766 bp
RNA expression pattern
	Top expressed in
	Skeletal muscle tissue of rectus abdominis; ; thoracic diaphragm; ; Skeletal muscle tissue of biceps brachii; ; triceps brachii muscle; ; gastrocnemius muscle; ; deltoid muscle; ; muscle of thigh; ; glutes; ; right ventricle; ; myocardium of left ventricle;
	Top expressed in
	digastric muscle; ; muscle of thigh; ; ankle; ; sternocleidomastoid muscle; ; medial head of gastrocnemius muscle; ; vastus lateralis muscle; ; skeletal muscle tissue; ; extraocular muscle; ; temporal muscle; ; triceps brachii muscle;
	More reference expression data
	n/a
Gene ontology
Molecular function	transferase activity; creatine kinase activity; transferase activity, transferring phosphorus-containing groups; nucleotide binding; catalytic activity; protein binding; ATP binding; kinase activity;
Cellular component	cytoplasm; cytosol; extracellular space;
Biological process	creatine metabolic process; phosphocreatine biosynthetic process; phosphorylation;
	Sources:Amigo / QuickGO
Orthologs
	1158
	12715
	ENSG00000104879
	ENSMUSG00000030399
	P06732
	P07310
	NM_001824
	NM_007710
	NP_001815
	NP_031736
	Wikidata
View/Edit Human	View/Edit Mouse

Creatine kinase, muscle also known as MCK is a creatine kinase that in humans is encoded by the MCK gene.^[5]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000104879 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000030399 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Rosenberg UB, Kunz G, Frischauf A, Lehrach H, Mähr R, Eppenberger HM, Perriard JC (November 1982). "Molecular cloning and expression during myogenesis of sequences coding for M-creatine kinase". Proc. Natl. Acad. Sci. U.S.A. 79 (21): 6589–92. Bibcode:1982PNAS...79.6589R. doi:10.1073/pnas.79.21.6589. PMC 347173. PMID 6959139.