CLCA3

CLCA3P
Identifiers
Aliases	CLCA3P, CLCA3, chloride channel accessory 3, pseudogene
External IDs	OMIM: 604337; GeneCards: CLCA3P; OMA:CLCA3P - orthologs
Gene location (Human)
Chr.	Chromosome 1 (human)
End	86,655,376 bp
Gene ontology
Molecular function	voltage-gated ion channel activity; chloride channel activity; calcium channel activity; transporter activity; metalloendopeptidase activity;
Cellular component	extracellular region; plasma membrane; chloride channel complex; extracellular space;
Biological process	calcium ion transport; ion transmembrane transport; regulation of ion transmembrane transport; chloride transport; chloride transmembrane transport; ion transport; calcium ion transmembrane transport; proteolysis;
	Sources:Amigo / QuickGO
Orthologs
	9629
	n/a
	ENSG00000153923
	n/a
	Q9Y6N3
	n/a
	NM_004921
	n/a
	n/a
	n/a
	Wikidata
View/Edit Human

Chloride channel accessory 3, also known as CLCA3, is a protein which in humans is encoded by the CLCA3P pseudogene. The protein encoded by this gene is a chloride channel.^[3] According to the HGNC, this protein is not expressed in humans but is in certain other species such as mouse. However, some conflicting reports state that human cells produce and glycosylate this protein.^[3]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000153923 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ ^a ^b Gruber AD, Pauli BU (March 1999). "Molecular cloning and biochemical characterization of a truncated, secreted member of the human family of Ca2+-activated Cl- channels". Biochimica et Biophysica Acta. 1444 (3): 418–23. doi:10.1016/S0167-4781(99)00008-1. PMID 10095065.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000153923 – Ensembl, May 2017

[2] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid10095065-3] Gruber AD, Pauli BU (March 1999). "Molecular cloning and biochemical characterization of a truncated, secreted member of the human family of Ca2+-activated Cl- channels". Biochimica et Biophysica Acta. 1444 (3): 418–23. doi:10.1016/S0167-4781(99)00008-1. PMID 10095065.

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