CLIC5

CLIC5
Identifiers
Aliases	CLIC5, MST130, MSTP130, DFNB102, DFNB103, chloride intracellular channel 5
External IDs	OMIM: 607293; MGI: 1917912; HomoloGene: 987; GeneCards: CLIC5; OMA:CLIC5 - orthologs
Gene location (Human)
Chr.	Chromosome 6 (human)
End	46,080,348 bp
Gene location (Mouse)
Chr.	Chromosome 17 (mouse)
End	44,591,059 bp
RNA expression pattern
	Top expressed in
	glomerulus; ; metanephric glomerulus; ; synovial joint; ; glutes; ; right ventricle; ; biceps brachii; ; Skeletal muscle tissue of rectus abdominis; ; germinal epithelium; ; Skeletal muscle tissue of biceps brachii; ; triceps brachii muscle;
	Top expressed in
	right lung; ; right lung lobe; ; left lung lobe; ; interventricular septum; ; myocardium of ventricle; ; ankle; ; triceps brachii muscle; ; vastus lateralis muscle; ; temporal muscle; ; epithelium of small intestine;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	protein binding; voltage-gated ion channel activity; glutathione transferase activity; chloride channel activity;
Cellular component	cell cortex; microtubule organizing center; cytoskeleton; chloride channel complex; actin cytoskeleton; integral component of membrane; membrane; extracellular exosome; Golgi apparatus; nucleus; cytoplasm; plasma membrane; apical plasma membrane;
Biological process	regulation of ion transmembrane transport; ion transport; hearing; female pregnancy; chloride transport; glutathione metabolic process; auditory receptor cell stereocilium organization; chloride transmembrane transport; transport; ion transmembrane transport; visual perception; response to stimulus;
	Sources:Amigo / QuickGO
Orthologs
	53405
	224796
	ENSG00000112782
	ENSMUSG00000023959
	Q9NZA1; Q53G01; Q49AE1
	Q8BXK9
	NM_001114086; NM_001256023; NM_016929; NM_001370649; NM_001370650
	NM_172621
NP_001107558; NP_001242952; NP_058625; NP_001357578; NP_001357579;
	NP_001107558.1; NP_058625.2; NP_001242952.1
	NP_766209
	Wikidata
View/Edit Human	View/Edit Mouse

Chloride intracellular channel protein 5 is a protein that in humans is encoded by the CLIC5 gene.^[5]^[6]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000112782 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000023959 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Berryman M, Bretscher A (May 2000). "Identification of a novel member of the chloride intracellular channel gene family (CLIC5) that associates with the actin cytoskeleton of placental microvilli". Molecular Biology of the Cell. 11 (5): 1509–1521. doi:10.1091/mbc.11.5.1509. PMC 14863. PMID 10793131.
^ "Entrez Gene: CLIC5 chloride intracellular channel 5".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000112782 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000023959 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid10793131-5] Berryman M, Bretscher A (May 2000). "Identification of a novel member of the chloride intracellular channel gene family (CLIC5) that associates with the actin cytoskeleton of placental microvilli". Molecular Biology of the Cell. 11 (5): 1509–1521. doi:10.1091/mbc.11.5.1509. PMC 14863. PMID 10793131.

[entrez-6] "Entrez Gene: CLIC5 chloride intracellular channel 5".

[1]

[2]

[3]

[4]

[5]

[6]